MSI Advances Next-Generation Data Center Infrastructure with AMD EPYC™ 9006 Series Server CPUs
Expanding AI, cloud, HPC, and enterprise capabilities through GPU, Core Compute, Open Compute, and enterprise server platforms
Taipei, Taiwan – November 11, 2026 – As agentic AI drives new demands for compute density, memory bandwidth, and data movement, MSI is advancing next-generation data center infrastructure with server platforms powered by AMD EPYC™ 9006 Series SP7 Server CPUs. With SP7 systems entering the shipping phase in Q4 2026 and SP8 platforms planned for the first half of 2027, MSI’s portfolio spans liquid-cooled GPU servers, 19” DC-MHS and 21” ORv3 multi-node platforms, and enterprise servers, supporting AI, cloud, HPC, virtualization, and business-critical workloads.
Built on the Zen 6 architecture, AMD EPYC 9006 Series Server CPUs deliver up to 256 cores and 512 threads per socket for high-density computing and AI agent execution. With up to 1.6TB/s of memory bandwidth and PCIe Gen6 connectivity, they support data-intensive workloads and high-speed I/O for GPUs, networking, and storage.
“As agentic AI reshapes data center workloads, infrastructure needs to evolve beyond compute performance alone,” said Danny Hsu, General Manager of MSI’s Enterprise Platform Solutions. “MSI’s AMD EPYC 9006 server platforms give customers the flexibility to align system architecture with their performance, deployment, and operational requirements.”
“Enterprise AI has moved from experimentation to production, and agentic AI will place even greater demands on compute, memory bandwidth, efficiency and system-level orchestration,” said Dan McNamara, senior vice president and general manager, Compute and Enterprise AI, AMD. “With 6th Gen AMD EPYC Server CPUs, AMD is helping customers scale enterprise AI with the performance and efficiency needed to support increasingly complex data pipelines, AI services and intelligent applications across the modern data center.”
Liquid-Cooled GPU Servers for AI Host Infrastructure
Designed for accelerator-rich AI infrastructure, the MSI CG681-S6093 6U liquid-cooled GPU server supports dual AMD EPYC 9006 Series Server CPUs and up to 8 liquid-cooled GPUs. With 32 DDR5 DIMM slots, PCIe Gen6 expansion, 400G networking, and 8 front-accessible E1.S NVMe drive bays, the platform provides the compute, memory, and I/O resources required for AI host-node deployments.
High-Density Multi-Node Computing
MSI’s 19” DC-MHS Core Compute platform delivers an air-cooled multi-node architecture for cloud, virtualization, and scale-out infrastructure. The SP7-based CD270-S4091-X2 features a 2U 2-node design with 16 DDR5 DIMM slots and 8 E1.S NVMe drive bays per node, supporting high-density compute within standard 19” rack environments.
Rack-Scale Computing with Open Architecture
MSI’s 21” ORv3 Open Compute platforms integrate DC-MHS multi-node architecture with 48Vdc busbar power distribution, supporting high-density compute through rack-level power delivery. Available in SP7 and SP8 configurations, the portfolio includes single-socket air-cooled designs and dual-socket air- and liquid-cooled options, up to 32 DDR5 DIMM slots per node, and E1.S or E3.S NVMe storage for diverse cloud, AI, and HPC deployments.
CD281-S4091-X2: 2OU 2-node, 1P SP7, air-cooled
CD282-S6091-X2: 2OU 2-node, 2P SP7, air-cooled
CD182-S6091-X2: 1OU 2-node, 2P SP7, liquid-cooled
CD281-S4081-X2: 2OU 2-node, 1P SP8, air-cooled
Flexible Enterprise Computing
MSI’s AMD EPYC 9006 Series SP8 enterprise servers offer balanced compute, memory, and I/O capabilities for virtualization, databases, storage, and business-critical workloads. Available in 1U and 2U single- and dual-socket configurations, the platforms support up to 32 DDR5 DIMM slots, PCIe Gen6 expansion, OCP 3.0 networking, and E3.S or U.2 NVMe storage options.
CD281-S4091-X2: 2OU 2-node, 1P SP7, air-cooled
CX172-S4081: 1U, 1P SP8
CX272-S4081: 2U, 1P SP8
CX172-S6082: 1U, 2P SP8
CX272-S6082: 2U, 2P SP8